More Than Methylation: The Crucial Role Of Choline With Dr. Jonathan Bortz

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March 23, 2020

In this episode, Dr Jonathan Bortz discusses his journey into developing pharmaceuticals and supplements, and how it brought him to look at choline in a different light. He talks about the story of choline as a “one carbon metabolism,” as well as the various uses of choline in the body, including its role in methylation, genetics, and non-alcoholic fatty liver disease (NAFLD).

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What's IF?

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November 25, 2019

Intrinsic Factor (IF) is a protein made in the stomach that is essential for ensuring the natural absorption of vitamin B12.

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Recombinant Protein Technology

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November 25, 2019

The gene for a human protein is inserted into the genetic code of other cells that can produce a protein that is identical to what is made in the body.

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Is Human Intrinsic Factor from humans?

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November 25, 2019

No! But it is human-derived because it is produced from the gene that makes human Intrinsic Factor.

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Growing the Plant

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November 25, 2019

The plant has become the factory for Intrinsic Factor.

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Extracting & Purifying

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November 25, 2019

The human recombinant Intrinsic factor is extracted by sophisticated pharmaceutical grade purification methods.

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Single Carbon metabolism - Choline, Folate and B12

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November 25, 2019

A balanced diet of B12, folate and choline is critical to ensuring the benefits of methylation (known as single carbon metabolism).

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B12 Deficiency

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November 25, 2019

There are many more people who don’t have enough B12 than we thought.

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