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1 Mathews, FS., et al;Crystal structure of human intrinsic factor: Cobalamin complex at 2.6-Å resolution. (2007) PNAS 104 (44) 17311-17316; https://doi.org/10.1073/pnas.0703228104

2Chanarin, I. Absorption of cobalamins. (1971) J Clin Path., 24 Suppler (Roy. Coll. Path) 5, 60-65

3Seetharam, B & Alpers, DH., Absorption and Transport of Cobalamin (Vitamin B12). (1982) Ann Rev Nutr. 2:343-69

4Heyssel, R., & al, e. (1966). Vitamin B12 Turnover in Man. Am. Journal of Clinical Nutr. , 18, 176-184.

5Bor MV., et al; Daily intake of 4 to 7 microg dietary vitamin B-12 is associated with steady concentrations of vitamin B-12-related biomarkers in a healthy young population. (2010) Am J Clin Nutr.91(3):571-7. doi: 10.3945/ajcn.2009.28082. Epub 2010 Jan 13.

6Bor, MV., et al; A daily intake of approximately 6 microg vitamin B-12 appears to saturate all the vitamin B-12-related variables in Danish postmenopausal women. (2006) Am J Clin Nutr. Jan;83(1):52-8.

7Arendt, J. F., et al; (2013). Elevated Plasma Vitamin B12 Levels as a Marker for Cancer: A Population-Based Cohort Study. Journal of National Cancer Institute , 105 (23), 1799-1805.

8Bor MV, et al. Holo-Transcobalamin Concentration and Transcobalamin Saturation Reflect Recent Vitamin B12 Absorption Better than Does Serum Vitamin B12. Clinical Chemistry. 2004; 50(6):1043-1049.

9Hvas, A., et alThe effect of recombinant human intrinsic factor on the uptake of vitamin B12 in patients with evident vitamin B12 deficiency. (2006) Haematologica. Jun;91(6):805-8.

10Data on File. Subset Analysis of 6 subjects with IF deficiency from Hvas (2006) cohort. (Xeragenx LLC.)

11Bonaccorso, RL., et al; Enhanced Peptide Stability Against Protease Digestion Induced by Intrinsic Factor Binding of a Vitamin B12 Conjugate of Exendin‐4. (2015) Mol Pharm. 12(9): 3502-3506.

12Clardy SL., et al; Vitamin B12 in drug delivery: breaking through the barriers to a B12 bioconjugate pharmaceutical. (2011) Expert Opinion Drug Deliv. 8(1):127-40.

13Workinger, JL., et al; Systemically Administered Plant Recombinant Holo-Intrinsic Factor Targets the Liver and is not Affected by Endogenous B12 levels. (2019) Sci Rep 9, 12269.

14Vortherms, AR., et al; A water soluble vitamin B12-Re(I) fluorescent conjugate for cell uptake screens: use in the confirmation of cubilin in the lung cancer line A549. (2011) Chem Commun. 47, 9792-9794.