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X Fact
June 16, 2020
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Complexity Rating

B12 is the Biggest and Most Complex Vitamin by Far

B12 is 3 times bigger than the next biggest vitamin (vit K) and 11 times bigger than the smallest (nicotinic acid or B3). It took an international collaboration of 19 countries, 103 scientists (from Harvard and the Swiss Institute of Technology) 12 years to synthesize it in 62 chemical steps. It is the most complex vitamin by far - it must be important.

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Who Wrote This X Fact
Jonathan Bortz MD
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Jonathan’s background as a practicing diabetes specialist for 15 years and 17-year career developing nutritional prescriptive products for the pharmaceutical industry has contributed to his ability to understand nutrients, how they work and why they are important.

Over the years he has acquired broad and in-depth knowledge in minerals, essential fatty acids and other nutrients, but has special expertise in Vitamin B12 and choline metabolism. He is often asked to speak at national and international venues to articulate why B12, folate and choline are so important to gene function, brain development, liver and cardiovascular health. He applies pharmaceutical standards to nutrient science and has developed a unique ability to translate complicated concepts into simple promotional messages that resonate with practitioners and consumers. He has developed dozens of innovative nutritional products, of which many are category leaders in the US. Jonathan obtained his medical degree from the University of the Witwatersrand Medical School in South Africa and did his fellowship in Endocrinology at Washington University in St. Louis, MO.

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