No items found.
X Fact
May 9, 2021
40 Second Read
Complexity Rating

Leveling the Playing Field with Choline.

A recent editorial published in the Schizophrenia Bulletin (Oxford University Press) dropped a bombshell that should not be ignored.  Researchers from the University of Colorado and their collaborators discussed their work over the past decade to study the relationship between prenatal choline and poorer outcomes of pregnancy including the development of mental illness in later life. The group designed a study to have participants self-identify as African American and found that when compared with women who identified as White from the same neighborhoods, socio-economic status, education and similar prenatal care, the African American women were more likely to have pre-term deliveries. Furthermore, the lower the maternal choline concentrations in pregnancy, the earlier the preterm delivery.

There is a lot to unpack from this study, and the reasons for the lower choline concentrations amongst African Americans does not have a clearcut and simple explanation, but the study points to a strong reason for early choline supplementation in pregnancy, just as folic acid supplementation has become synonymous with good prenatal care. Low maternal choline levels is significantly associated with fetal neurodevelopment in all populations but the authors are sounding a warning that the offspring of African Americans could be particularly at risk ".... beginning with lower gestational age at birth."

Words You May Not Know
No items found.
Who Wrote This X Fact
Jonathan Bortz MD
Bio Quick View

Jonathan’s background as a practicing diabetes specialist for 15 years and 17-year career developing nutritional prescriptive products for the pharmaceutical industry has contributed to his ability to understand nutrients, how they work and why they are important.

Over the years he has acquired broad and in-depth knowledge in minerals, essential fatty acids and other nutrients, but has special expertise in Vitamin B12 and choline metabolism. He is often asked to speak at national and international venues to articulate why B12, folate and choline are so important to gene function, brain development, liver and cardiovascular health. He applies pharmaceutical standards to nutrient science and has developed a unique ability to translate complicated concepts into simple promotional messages that resonate with practitioners and consumers. He has developed dozens of innovative nutritional products, of which many are category leaders in the US. Jonathan obtained his medical degree from the University of the Witwatersrand Medical School in South Africa and did his fellowship in Endocrinology at Washington University in St. Louis, MO.

Top Picks
Recent X Facts